10  Advanced Systemic Mastocytosis

10.1 SM-AHN

• 75% of SM are SM-AHN

10.1.1 HSCT in SM-AHN

• Limited graft vs mast cell effect so need to control mastocytosis before recommending HSCT for AHN component

• Initial literature published in 2014 Ustun et al. (2014)
• German registry data at ASH 2023 Christen et al. (2023)

Christen, Deborah, Johannes Lübke, Anne Kaiser, et al. 2023. “Allogeneic Hematopoietic Stem Cell Transplantation in Advanced Systemic Mastocytosis.” Blood 142 (Supplement 1): 3605–5. https://doi.org/10.1182/blood-2023-178304.

Ustun, Celalettin, Andreas Reiter, Bart L. Scott, et al. 2014. “Hematopoietic Stem-Cell Transplantation for Advanced Systemic Mastocytosis.” Journal of Clinical Oncology 32 (29): 3264–74. https://doi.org/10.1200/jco.2014.55.2018.